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m J Physiol Endocrinol Metab

In addition to physical exertion, fatigue can be brought on by conditions like arthritis, anemia, fibromyalgia, chronic fatigue syndrome, colds, flu, eating disorders, sleeping problems, autoimmune disorders, and diabetes

At the same time, reviewers note that evidence for many of AOD9604's proposed effects in humans remains limited and preclinical, and the pivotal human efficacy trial did not confirm the weight-loss signal seen in the earlier, smaller study

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Treatment is typically lifelong for patients with pernicious anaemia or irreversible malabsorption conditions