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The relevance of this enzyme is illustrated by the fact that global SOD2 deficiency leads to neonatal death in mice (Huang et al., 1997)

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While some patients experience reversible hearing impairment upon drug discontinuation, prolonged exposure can lead to progressive damage, particularly in individuals with preexisting auditory conditions

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Ahmed Frontiers in Bioscience-Landmark.2025;[Epub] CrossRef Immunosenescence and cancer: molecular hallmarks, tumor microenvironment remodeling, and age-specific immunotherapy challenges Qianwen Liu, Jingfeng Li, Xiuqiao Sun, Jiayu Lin, Zhengwei Yu, Yue Xiao, Dan Li, Baofa Sun, Haili Bao, Yihao Liu Journal of Hematology & Oncology.2025;[Epub] CrossRef Correlation Between the Proportion of Senescence-Associated -Galactosidase-Stained CD8+ T Cells and Age: A Cross-Sectional Study in Japan Masaya Tsubokawa, Yoshiki Shimizu, Misato Yazaki, Shieri Shimodan, Masayuki Noguchi, Arisa Yamazaki, Tomomichi Watanabe, Makoto Ocho, Tsuyoshi Sakurada, Yoshie Hirose, Jiro Saito, Yuri Ishii International Journal of Molecular Sciences.2025