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Those with naturally high NNMT activity might respond more dramatically to inhibition, while those with lower baseline activity might see more modest effects

A threshold that doesn't trigger clinical deficiency symptoms but correlates with persistent fatigue, brain fog, and impaired fat metabolism
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However, its important to note that B12 injections can have side effects, although these are generally rare

B12 is a co-substrate of various cell reactions involved in methylation synthesis of nucleic acid and neurotransmitters

There are many GLP-1 medications
