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Once-monthly maridebart cafraglutide for the treatment of obesitya phase 2 trial
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GLP-1RAs reduce events linked to atherogenic cardiovascular disease (especially ischemic stroke) and also renal outcomes (FLOW trial with semaglutide), with a limited effect on heart failure
Understanding whether similar adaptive processes influence therapeutic efficacy related to alcohols interoceptive effects will be an important area for further research
Some benefits of GLP-1s occur independently of weight loss, so multiple factors are likely in play
