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PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland development
It is able to cause the cell membrane gap so as to be invaded by germs and virus which further damage the karyotheca, expose, damage the genetic materials and even cause mutation

However, several other studies do not show a similar increase in cancer risk [1219]

& Korthuis, R

doi:10.1186/s12958-018-0323-4 [51] Venkatesan P
