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This strongly suggests that earlyonset cases are more likely mediated by topdown mechanisms, driven by a stronger genetic/neurobiological vulnerability to central dysregulation

Brain Research, 1542, 2031

doi: 10.1038/s41392-023-01438-z 128 ZhaoH.ChuM.HuangZ.YangX.RanS.HuB.et al

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The vaccines developed by Pfizer and Moderna both include genetic material consisting of messenger RNA (mRNA) particles that encode for the spike protein from the COVID-19 vaccine encased in a lipid nanoparticle (tiny fat bubble) that allows the mRNA to remain intact and keep the fragile mRNA from being degraded

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