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Pharmacol Res 51:319327 Kosenko E, Llansola M, Montoliu C, Monfort P, Rodrigo R, Hernandez-Viadel M, Erceg S, Snchez-Perez AM, Felipo V (2003) Glutamine synthetase activity and glutamine content in brain: modulation by NMDA receptors and nitric oxide
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During cancer cachexia, mitochondrial dysfunction also plays a role in muscle atrophy
10.1056/NEJMoa042976 69 DengS.YanT.NikolovaT.FuhrmannD.NemecekA.Gdtel-ArmbrustU.et al (2015)
This binding initiates an intracellular signaling cascade, promoting gene expression related to cell survival, proliferation, and migration, ultimately leading to the formation of new capillary networks and enhanced tissue perfusion
