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MGO is linked to microvascular dysfunction, and maintaining the integrity of the bloodbrain barrier (BBB) is essential for optimal brain function [267]

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227 In an in silico screen to identify inhibitors of the Rac1p67 phox interaction, a fundamental step in NOX2 activation, compound 16 (Phox-I1) was identified as a new NOX2 inhibitor

PMID 23782759

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