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Results: The AI method showed almost perfect agreement with neuroradiologists in detecting severe MLS ( = 0.87) with 95.2% correctly classified cases among all cases, and = 0.84 with 92.0% accuracy among MLS cases

This method offers several advantages over other routes of administration, such as oral or intramuscular, including faster onset, higher bioavailability, and the ability to administer substances that may be poorly absorbed or tolerated by other routes

higher or twice-daily dosing uses more

Bello S, Bonali C, Serafino L et al (2014) Intra-articular therapy with tumor necrosis factor-alpha antagonists: an update

This is a stressor for the body, causing hypoxia of intestinal cells due to redistribution of blood in the body, hyperthermia and dehydration [158, 159]