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These effects appear to be mediated primarily through activation of phosphodiesterase 3B (138)

If you could isolate just the C-terminal domain responsible for fat oxidation, you might have a clean metabolic agent

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Adult male C57BL/6 mice on a 60% kcal-from-fat high-fat diet received intraperitoneal or oral 5-Amino-1MQ at amounts in the milligram-per-kilogram range or vehicle, over an 11-day treatment period in the published protocol

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