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Some of the important diseases in which oxidative stress and inflammation play an important role are: coronary heart disease (CHD) hypertension metabolic syndrome diabetes kidney dysfunction pulmonary insufficiency atherosclerosis rheumatoid arthritis inflammatory bowel disease neurodegenerative diseases such as Alzheimers, Parkinsons and ALS age-related macular degeneration Oxidative stress is also thought to be involved in: ADHD, cancer, sickle-cell disease, lichen planus, vitiligo, autism, infection, chronic fatigue syndrome, depression and Aspergers syndrome