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Additionally, manufacturers must address operational complexities, demanding contamination controls, and the need for highly specialized fill-finish expertise and equipment

Efficacy and safety of the human GLP-1 analog liraglutide in combination with metformin and TZD in patients with type 2 diabetes mellitus (LEAD-4 Met+TZD)

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Torres Fernandez ED, Huffman AM, Syed M, Romero DG, Yanes Cardozo LL

Generally a BMI of 30+, or 27+ with a weight-related condition such as high blood pressure, type 2 diabetes, high cholesterol, or sleep apnea
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