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Impact of manufacturing process and compounding on properties and quality of follow-on GLP-1 polypeptide drugs

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smegmatis To further validate the role of Thr219Thr221 residues in SahH phosphorylation, we mutated these residues simultaneously in pYUBDuet-SahH and over-expressed SahH-T219A/T220A/T221A in M

Optimization and standardization of reliable protocols are crucial to obtain meaningful results

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Given the fact that anticoagulation can regulate AILI both positively and negatively, therapeutic strategies targeted on hemostatic system remain uncertain and need to be addressed in the future