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CTLA-4 expressed by Tregs downregulates the surface expression of CD80 and CD86 on antigen-presenting cells (APCs) such as dendritic cells (DCs) and B cells, thereby withdrawing CD28-mediated costimulatory signals in responder T cells [23,24,25,26]

Here are the six most common root causes: The microbiomeboth in the gut and on the skinplays a key role in regulating inflammation and supporting the immune system

Pages 833-879 in Sturkie's Avian Physiology

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[DOI] [PMC free article] [PubMed] [Google Scholar] Luo J
