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Cysteine is found in the lowest concentrations of the trio required to make GSH
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[50] found that activated ERK1/2 played a pro-apoptotic role by inducing BAX expression, MMP depolarization, mitochondrial Cyto-C release and caspase3 upregulation, which was in line with our findings
Furthermore, by using a luciferase reporter system with a UGA codon inserted in the protein coding region of the luciferase reporter gene, we confirmed that selenium-dependent expression was independent of the GPx1 promoter [68]
Glutathione is naturally present in high concentrations in lung tissue, where it helps protect against respiratory stress
