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It is worth noting that bioavailability research, by dynamically characterizing the in vivo fate and systemic exposure of complex TCM components, has become a pivotal bridge for evaluating the clinical efficacy and safety of TCM in line with its holistic nature [8]

Warming vials to speed dissolution risks heat damage

20 mM HEPES, 50 mM NaCl, pH 7.4, 1 Complete Protease inhibitor cocktail (Roche)

3 Htel Dieu, Pharmacie Clinique, Nantes, France

Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration

Nevertheless, subsequent deprotonation of the analyte by counterion neutralization is thermodynamically unfavorable because the acidity of the carboxylic acid groups of peptides and proteins is lower than that of common counterions (such as trifluoroacetic acid (TFA) or chloride)