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A study involved pretreating poly(I:C)-injected mice mothers with anti-IL-17a-monoclonal antibodies to induce MIA via cytokine release, was reported to partially alleviate abnormal social interaction difficulties and repetitive behaviors and preserve normal cortical development in MIA offspring [71]

This work was funded by the NIH (K22ES012264, R01CA152063 R01CA241554), a Voelcker Fund Young Investigator Award, CPRIT (RP150445), Stand Up 2 Cancer-Cancer Research UK (RT6187) and GCCRI pilot funds to A.J.R.B

Paradoxically, while angiogenesis is initiated to alleviate hypoxia, the resulting vasculature frequently fails to resolve oxygen deficiency, thereby creating a vicious cycle of persistent hypoxia and continued HIF activation (165)

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Moriuchi H, Moriuchi M, Fauci AS: Nuclear factor-kappa B potently up-regulates the promoter activity of RANTES, a chemokine that blocks HIV infection