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Experimental studies have shown that inhibition of miR-34a in mice fed an HFD increases PPAR expression and AMPK activation, which promotes fatty acid -oxidation and reduces TG accumulation in the liver [300]

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The effects of NPs on lung cancers (both primary and metastatic) were shown by increased drug delivery to selective lung cancer and lung metastases locations, as well as by increasing efficacy on lung cancer cells

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There are very few experiments that have been undertaken with such dosages on humans

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