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The new stomach pouch is so small that there is a decrease in gastric acid

Blood tests measure serum creatinine and calculate eGFR to assess filtration capacity, while urinalysis detects proteinuria, hematuria, and tubular casts

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Thus, these compounds are generally well studied, and the more rational understanding of the mechanism of their nephrotoxicity in animals and man provides the basis for validating extrapolation between species and making rational risk assessment