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It also tends to promote the release of histamine, leading to adverse reactions such as rashes and gastrointestinal distress, which limits its wide-spread use in the management of the disease (4)

People with a history of seizures or epilepsy face the highest risk
Pollari et al., 2011

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Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimers disease
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