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doi: 10.3389/fimmu.2025.1530301 Received 18 November 2024 Accepted 31 March 2025 Published 16 May 2025 Volume 16 - 2025 Edited by Sudhir Gupta, University of California, Irvine, United States Reviewed by Hridesh Banerjee, University of Pittsburgh, United States Gul Ahmad, Peru State College, United States Updates Copyright 2025 Shi, Yu, Xie, Yin, Chen, Zhao and Zhao

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The lack of effectiveness of traditional antipsychotic therapy, especially in the treatment of negative and cognitive symptoms, leads to the search for new therapeutic avenues