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The population frequency of the rs1801222A allele is 20%, ranging from 15% in East Asians to 29% in Europeans [31], suggesting that the variant will impact all population groups treated with metformin
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doi:10.1093/jn/138.1.130 Tutelyan VA, Makhova AA, Pogozheva AV, Shikh EV, Elizarova EV, Khotimchenko SA

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