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First, whether doses larger than 2.88 mg/kg would further improve MWM performance is worth exploring in future studies

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Although we were unable to assess many potential confounders, sensitivity analysis using E-values showed that unmeasured confounders would need to be larger than observed effects of several known relevant variables to explain away all observed effects in these models

8.4 Adjunctive application of probiotics and synbiotics 8.4.1 Evidence hierarchy in probiotic/synbiotic interventions for DKD The therapeutic potential of probiotics and synbiotics in DKD management is supported by a hierarchical body of evidence spanning mechanistic studies to clinical trials