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Frequently, brain tumor and its therapy are endocrinologically devastating for children, and the most common residua are growth failure or short stature, which may be caused by the high rate of GHD in children after cranial radiation and radiation effects on skeletal growth after spinal or whole-body radiation treatment (Schriock et al., 1991)

Interestingly, confirming the key role of intestinal barrier damage in metabolic disease, positive results come from the use of Lubiprostone (LUB) in NAFLD: it is a bicyclic fatty acid, usually used in constipation, which has the ability to promote intestinal fluid secretion

A high-resolution ICP-MS method for the determination of 38 inorganic elements in human whole blood, urine, hair and tissues after microwave digestion

Likewise, human OA chondrocytes, which express the GHR, were resistant to hGH treatment as evidenced by its lack of effects on cell viability, metabolic activity, collagen type 1 or 2, and even IGF-1 or 2 gene expression [176]

Vitamin C is a powerful antioxidant that not only boosts the immune system, but also promotes the production of collagen, which is vital for skin health and wound healing

Similarly, high-dose intraperitoneal NAC injections caused microglial mortality in the brains of mice