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With the right choices, youll protect your muscles, keep your energy up, and make every bite count while GLP-1s do their job

Regulating Satiety Pathways: In the hypothalamus, GLP-1 RAs stimulate neurons that promote satiety (POMC/CART neurons) and inhibit neurons that drive hunger (NPY/AgRP neurons), reducing food intake and enhancing fullness (Zheng et al., 2024)

In the HARMONY-2 (efficacy and safety of once-weekly GLP-1 receptor agonist albiglutide) clinical study, patients were randomized to receive either once-weekly albiglutide (30 mg, titrated up to 50 mg if required for glycemic control) or 10 units of insulin glargine once daily
A., Heerspink, H
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Rats were acclimated to the experimental conditions by daily handling during 7 days