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They are commonly used in patients with rheumatoid arthritis (RA), SLE, discoid lupus erythematosus, polymorphous light eruptions, solar urticaria, recurrent basal cell carcinoma of the skin, porphyrea cutane tarda, antiphospholipid antibody syndrome, and more than 20 other rarer conditions [11, 1620]

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Measure testing found that assessing radiation doses and providing audit feedback to radiologists resulted in significant reductions in excessive and unsafe dose levels

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Gain-of-function mutations in oncogenes (such as RAS superfamily) or positive regulators (such as NF-B inducing kinase) contribute to sustained activation of NF-B signaling and subsequent cell proliferation

Increasing evidence suggests that ACSL4 is a critical factor for ferroptosis sensitivity (Doll et al., 2017