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R.GowanK.RiccardiS

[PubMed] [Google Scholar] 190

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In patients with chronic or neuropathic pain, microglia can become chronically activated, releasing inflammatory signals that amplify pain

This response is associated with dysregulation of histone H3 lysine 4 trimethylation (H3K4me3) and increased expression of genes involved in metabolism and inflammation (88)
