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Although these strategies enhance the delivery of drugs to the brain through ligand-receptor interactions, they have limitations, such as dependence on high receptor expression and the potential for immune responses or receptor downregulation

Glucocorticoids also act to increase blood glucose levels by inhibiting glucose uptake (also primarily at the level of adipose tissue and skeletal muscle) and by stimulation of gluconeogenesis

[PMC free article] [PubMed] [Google Scholar] 715.Kido, J., Sugawara, K

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No single gene is the causative agent

Nuclear receptor coactivator 4 (NCOA4) serves a role in ferritin degradation, helping to maintain intracellular iron balance by modulating ferritin autophagy (30)
