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For a newborn, it might mean they cannot go more than 3-4 hours without feeding (meaning you must wake them up at night)

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[DOI] [PubMed] [Google Scholar] [85].Boudreau DM, Yu O, Johnson J

We thus observed a slight improvement of the physiological parameters of the worms, which, however, was significantly lower than that observed upon treatment with vesicles loaded with DesAb-F (Figure S7)

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Therefore, we will also provide a brief overview of experimental approaches and discuss how to utilize them for a more critical interpretation of the data in this field