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This review examines the complex mechanisms underlying MTX-induced liver damage, including oxidative stress, mitochondrial impairment, inflammatory signaling pathways such as NF-B and JAK/STAT, and apoptosis

Cardamonin Cardamonin (CAR) is a chalcone isolated from Alpiniae katsumadai

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[DOI] [PMC free article] [PubMed] [Google Scholar] 1096.Song F., Hurtado del Pozo C., Rosario R., Zou Y.S., Ananthakrishnan R., Xu X., Patel P.R., Benoit V.M., Yan S.F., Li H., et al

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Expert Rev Mol Med (2009) 11:e13