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After reaction with secondary antibodies, tissue slides were processed with Vector ABC Kit (Vector Laboratories)

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Night-time is when the body naturally focuses on repair, recovery, and cellular regeneration

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Furthermore, a better understanding of the molecular mechanisms involved in airway infection and inflammation in CF has led to the development of new therapeutic approaches that are currently under evaluation by clinical trials

This results in the accumulation of a large number of unfolded or misfolded proteins in the ER, thereby activating the ERS response (Luo et al., 2023)