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1 In vitro studies conducted in Vero cells were excluded because of the inability for these cells to produce type I interferon responses, making them unsuitable for assessing the immunomodulatory effects of HCQ and CQ

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Non-isomorphous data readily yielded the initial structure by molecular replacement using an internal proprietary crystal structure

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In AD models, it suppresses astrocytic STAT3 activation, reducing A-induced neuronal death (275)

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