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Silencing this gene can decrease Bcl-2 expression and increase Bax protein expression, leading to a reduced Bcl-2/Bax ratio, thereby promoting prostate cell apoptosis [38]

[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Garca-Montero C., Ortega M.A., Alvarez-Mon M.A., Fraile-Martinez O., Romero-Bazn A., Lahera G., Montes-Rodrguez J.M., Molina-Ruiz R.M., Mora F., Rodriguez-Jimenez R., et al

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The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition