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PDHC activation also restored anabolic energy in inflammatory monocytes while also increasing the abundance of TCA cycle intermediates and the anaplerotic metabolism of branched-chain amino acids, thus promoting TCA-driven anabolic energetics (47)

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Amylin signaling is closely connected to nutrient handling, gastric motility, and postprandial metabolic responses, which makes cagrilintide relevant in experimental models examining glycemic control and endocrine-metabolic communication [1]

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