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The link between GSTs and the MAP kinase pathway provides a rationale as to why in many cases the drugs used to select for resistance are neither subject to conjugation with GSH, nor substrates for GSTs

Therefore, screening for lead compounds able to activate this essential enzyme might protect neuronal cells from damage and slow the disease progression

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This method encapsulates the glutathione in protective phospholipids, ensuring it passes through the digestive system intact and is efficiently delivered into systemic circulation and directly to the cells where it is needed most