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doi: 10.1016/j.pcl.2018.08.006 7 CaridiGTrivelliASanna-CherchiSPerfumoFGhiggeriGM

Endogenous Derivatives of Linoleic Acid and Their Stable Analogues Are Potential Pain Mediators

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This is due to its ability to readily oxidize and modify lipids, proteins, and nucleic acids, which are vital for biological functions, thereby causing their loss of function through Diels-Alder reactions
