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Description
Ribonucleotide reductase regulatory subunit M2 (RRM2, a structural unit essential for DNA replication and repair) maintains intracellular GSH by protecting GLC from degradation to exert an anti-ferroptosis effect (Yang Y

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The repeating disaccharide units are identified as type A and type B ulvanobiuronic acid 3-sulfate [101]

[DOI] [PMC free article] [PubMed] [Google Scholar] MacDonald, M.E., Pike, G.B., 2021

Disturbances in GSH homeostasis are related to the etiology and/or progression of a variety of diseases besides the CVD listed in this work, such as cancer [163,164] diabetes [165,166,167], cystic fibrosis [168,169], Parkinsons disease [170,171,172], Alzheimers disease [173,174], as well as inflammatory [175], immune [176,177], metabolic [178], and neurodegenerative diseases [179,180], among others
