summit clinical trial tirzepatide SUMMIT: Benefits From Similar By Sex in Patients With Obesity-Related HFpEF In the SUMMIT trial, researchers
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Retatrutide Phase 2 (Jastreboff et al., NEJM 2023) reported 24.2% weight loss at 48 weeks at 12 mg

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Bibcode:2015PLoSO..1040908A

doi: 10.1038/ijo.2016.185
while in rats it is highly expressed in the C-cells of this organ, there appears to be little detectable expression in non-human primate and human C-cells (85, 88)