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It has been shown that many types of cells can trap NAC, hydrolyze it and change it into L-cysteine, which is then incorporated into the cycle of gamma glutamyl, stimulating glutathione synthesis [58]

The risk of MDD was even higher in people who also had COMT slow (MET) alleles

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doi: 10.3389/fcell.2015.00083 37 VermotAPetit-HrtleinISmithSMEFieschiF

Subsequent sections will provide a detailed analysis of how MPs/NPs exacerbate PD progression through specific pathways: promoting aberrant -synuclein aggregation, inducing neuroinflammation, disrupting gut-brain axis homeostasis, interfering with mitochondrial energy metabolism, inhibiting the excitatory amino acid transporter 2(EAAT2), and triggering ferroptosis

De Felice FG, Vieira MN, Bomfim TR, Decker H, Velasco PT, Lambert MP, et al