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Description
Oxylipins were quantified using UHPLCMRMMS/MS on an EXIONLC System (SCIEX) coupled to a SCIEX 6500 QTRAP+ mass spectrometer equipped with an IonDrive Turbo V electrospray ionization (ESI) source
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Fetal bovine serum: risk management

Over the past few years, results from clinical trials of IMiDs in MM patients have shown that the presence of conferring resistance mutations, loss of gene copy and splice variants of cereblon are associated with resistance to IMiDs and worse clinical outcome 192,193
Elevated IGF-1 levels: Serum IGF-1, the downstream marker of growth hormone activity, rises with consistent Sermorelin administration

Volcano plots showing differential protein and PTM related to HDAC or HATs in C4 (n = 16 patients) and C8 (n = 16 patients) compared to other subtypes
