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307 However, in a randomized controlled trial in 72 women with fibromyalgia, those assigned to MSG and aspartame elimination had no greater decrease in symptoms than those in a control group assigned to a waiting list

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In the absence of controlled study data, no definitive recommendations can be made in regard to the timing of treatment initiation, but it seems reasonable to delay treatment for 2 to 4 months after acute onset to allow for spontaneous resolution (II-3) 44
