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Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

Target validation: Comparison of target predictions with observations from previous literature As an initial validation, several of the genes in Table 1 were identified as proven drug targets in the literature and some have previously identified inhibitors in Leishmania or other related species

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19, 20 Changes in many of these molecules were consistently observed in another cohort for early psychosis