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4.5 GM-Based Interventions: Potential Use as Disease-Modifying and Preventive Treatments To date, studies testing GM-based interventions have been conducted in groups of patients with manifest PD, with the main goal to treat symptoms

5 shows that glutathione is produced in a separate reaction from the methionine cycle

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J Appl Physiol 63:152157 Huang J, Philbert MA (1995) Distribution of glutathione and glutathione-related enzyme systems in mitochondria and cytosol of cultured cerebellar astrocytes and granule cells

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Decreased endogenous antioxidant capacity, particularly reduced total glutathione (tGSH) levels and altered glutathione peroxidase (GPx), superoxide dismutase, and catalase activities, have been reported in ASD, which is consistent with elevated oxidative stress indicators in children with ASD