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In controlled research environments, observed effects are generally linked to receptor activation across different systems, including: Pigmentation pathways (MC1R) Neuroendocrine signaling (MC3R, MC4R) Peripheral physiological responses These interactions may lead to a range of observable responses, depending on study design, dosage, and individual variability

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elegans , blocking receptors sites and reducing pathogen colonization (89)

doi: 10.1021/acschemneuro.2c00330