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[DOI] [PMC free article] [PubMed] [Google Scholar] 125.Kabil O, Motl N, Banerjee R
An exemplary case of MRTX849, a covalent inhibitor targeting KRAS G12C mutant, benefited from a lower reactivity warhead with an additional fluorine at the acrylamide -carbon position, thus achieving better metabolic stability [113]
