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DieboldSMoellmannJKahlesFHaj-YehiaELiehnEANickelAet alMyocardial infarction is sufficient to increase GLP-1 secretion, leading to improved left ventricular contractility and mitochondrial respiratory capacity

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This dual-pathway stimulation is observed in research to produce a robust, physiological pulse of Growth Hormone (GH) without the significant elevation of cortisol or prolactin often seen with non-selective secretagogues like GHRP-2 or GHRP-6

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In rodent models with dopaminergic lesions resembling Parkinsons conditions, it improved behavioural outcomes and showed neurorestorative effects on surviving neurons