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Loperamide induced excessive ER-phagy to cause cell death [38], while it also eliminated lysosomes during LMP through lysophagy [47], suggesting that autophagy may be involved in different processes in the same cells

doi: 10.1111/j.1476-5381.2011.01480.x 162 Rodrguez-CampuzanoAGOrtegaA

Nucleic Acids Research, 40(D1), D700D705

Its also increasingly studied for its role in neurological health and metabolic conditions

doi: 10.3389/fmed.2026.1730795 Received 23 October 2025 Revised 06 March 2026 Accepted 23 March 2026 Published 02 April 2026 Corrected 05 June 2026 Volume 13 - 2026 Edited by Andrea Tinelli, Veris Delli Ponti Hospital, Italy Reviewed by Feng Zhang, Nanjing University of Chinese Medicine, China Minghong Sun, Southwest University, China Updates Copyright 2026 Lv, Li, Ding and Kuang

Therefore, we preliminarily propose that functional lncRNAs targeting the miR-128-3p/ CSF1 regulatory axis may be present in serum-derived EXOs in PCOS