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Their clearance involves cellular protein degradation processes, during which a portion of AGE is hydrolyzed into AGE peptides

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At 72 hours, cells were imaged under brightfield microscopy, and cells were lysed with Trizol Reagent (Thermo Fisher Scientific, Halethorpe, MD)

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Studies examining the differential effects of Melanotan 1 on eumelanin vs phaeomelanin production have contributed to the broader understanding of how MC1R signalling quality and duration influence pigmentation type relevant to research examining MC1Rs role in UV photoprotection biology