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To date, two small molecule c-MET inhibitors, cabozantinib and crizotinib, have been approved by regulatory authorities for the treatment of selected cancer types, but several novel c-MET inhibitors (either monoclonal antibodies or small molecule c-MET tyrosine kinase inhibitors) and treatment combinations are currently under study in different settings

Stremmel W, Weiskirchen R

Inflammation and Oxidative Stress Research Studies suggest that the peptide may support oxidative stress pathways, metal ion homeostasis, and anti-inflammatory gene networks

doi: 10.1042/BST20060223

G-Protein-Coupled Receptors and Ischemic Stroke: a Focus on Molecular Function and Therapeutic Potential

These insights emphasize that PD is not solely a brain disorder but involves multisystem interactions that influence disease onset and progression