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Description
They can participate in cell proliferation, migration, differentiation, cell barrier formation, programmed cell death, hypoxia/reoxygenation injury and other cellular functions and metabolic processes (118-120)

pneumophila modulates the energy level of host cells to create an environment permissive for its growth

Functions through direct binding to PPARd ligand-binding domain, modulating gene transcription via PPAR response elements (PPREs)

doi: 10.1016/j.tifs.2022.03.020 [DOI] [Google Scholar] 20.Albuquerque PBS, de Oliveira WF, Dos Santos Silva PM, Dos Santos Correia MT, Kennedy JF, Coelho L

doi:10.1016/j.emc.2008.09.002 Susanto M

Finally, we will discuss the possible implications of these data for a better understanding of opioid reward and heroin addiction
